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While the GH increase from CJC-1295/Ipamorelin is more modest than pharmaceutical GH replacement, it operates through the same pathway and avoids the side effect profile associated with exogenous GH administration

Science 2006;311, 1257 34

This multi-state binding model explains the endothermic phase as the states coordinating one or two histidine residues have a lower enthalpy of binding than those with three or four histidine residues coordinated

It helps regulate the bodys sleep cycle, making it easier to fall asleep and stay asleep without the grogginess or dependency associated with traditional sleep aids

It is also used in some hair growth products

It particularly and consistently interacts with the NO-system, in various models and different species (4, 8, 25-27)