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Its five main mechanisms of action are as follows: (1) Increases the threshold for migraine attacks by activating different sites on the gamma-aminobutyric acid (GABA) receptors in brain neural tissue, decreasing neuronal excitability, boosting membrane hyperpolarization, and decreasing focal discharges

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From a systems-based perspective, improving packaging to facilitate calculation and delivery of an appropriate dose may be a practical intervention.17 It may also be useful to have childrens acetaminophen behind the counter so that parents are counselled by a pharmacist before purchasing the medication