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Subsequent structural studies provided detailed insights into how FcRn-specific Fab fragments could mask the IgG Fc-binding site on FcRn [123]

Mertschenk B, Beck F, Bauer W (1995) Thiourea and thiourea derivates

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At the same time, it should be emphasized that this effect is strongly dependent on the dose and the patients initial selenium status, as both selenium deficiency and excess can lead to adverse disease outcomes [15]