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This modification of bleomycin can potentially reduce harmful side effects, offering a promising development in cancer treatment [61]

Aging Cell 6 , 111119 (2007)

Whether all iron- and 2-OG-dependent enzymes require PCBPs for their metallation and activation remains undetermined

As proof of principle, an association between some autoimmune diseases and NF1 has been reported, 109 most likely as a result of enhanced immune function due to NF1 heterozygosity