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Ceramide promotes apoptosis in Chronic Myelogenous leukemia-derived K562 Cells by a mechanism involving caspase-8 and JNK

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Morphine treatment will result in changes of a series of intracellular signaling pathway, such as adenylate cyclase/cAMP/protein kinase A, phospholipase C/protein kinase C, phosphatidylinositol 3-kinase/Akt, and glycogen synthase kinase 3

This lets them float, sink, or maintain a steady depth