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8l), mitochondrial NADPH (Fig

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Ionic mechanisms of cell death induction/protection involving TRPM2 and TRPM7 Since cell death induction is tightly coupled to dysfunction of cell volume regulation, in which TRPM2 and TRPM7, as already described, play important roles, the ionic mechanisms of cell death induction may, at least in part, involve TRPM2 and TRPM7 channel activities in relation to altered mechanisms of the cell volume regulation

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CD147 inhibitors lead to intracellular retention of MCT1/4, disrupting lactate transport and intercellular lactate exchange [55]