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Lactobacillus rhamnosus GG and Bifidobacterium longum are among the most studied strains for gut lining repair, specifically because of their ability to reinforce tight junctions and reduce intestinal permeability markers in clinical trials (NIH)

In melanoma, a study utilized endogenous copper ions and click chemistry cascade reactions to successfully amplify the cuproptosis effect, effectively inhibiting tumor growth (Liu et al., 2025)