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For the last 20 years, Sekhar has been studying natural aging in humans and animal models to understand why age-related declines occur and how to correct them

Marine collagen excels at structural support, reducing wrinkles, and improving firmness, while glutathione leads in brightening, antioxidant protection, and evening skin tone

Large expression differences in genes for iron and zinc homeostasis, stress response, and lignin biosynthesis distinguish roots of Arabidopsis thaliana and the related metal hyperaccumulator Thlaspi caerulescens

*Correspondence: Jin-Song Bian, [email protected] This article was submitted to Translational Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Notably, macrophage-derived TNF- plays a role in modulating ferroptosis susceptibility in cellular populations

Endoplasmic Reticulum Stress Modulation Different damaging factors may affect intracellular pathways by impairing correct proteins turnover, resulting in accumulation of unfolded and misfolded proteins in the lumen of endoplasmic reticulum (ER)