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Rational protein design yields a CD20 CAR with superior antitumor efficacy compared with CD19 CAR

For instance, the expression of ChR2 in Purkinje cells, which can be induced using transgenic mutant mice, by in utero electroporation or by viral injections [107], allows precise control over action potential firing in their downstream target, the cerebellar nuclei [108] and thereby over cerebellar-evoked excitation or inhibition in the thalamus

The microbiome and autoimmunity: a paradigm from the gut-liver axis

Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization

Quintero-Villegas A, Valds-Ferrer SI

In the Phase 2 trial, the cohorts that escalated to higher maintenance doses began at 2mg weekly and increased by 2mg every 4 weeks