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And, if you inhibit the enzyme (lowering its Vmax), the Hcy concentration will drop so the flux through CBS remains the same at steady state

10.1194/jlr.D700041-JLR200 J

What about the fact that it's coming out so clearly with this group

Fourier-transform infrared spectroscopy (FTIR) The FTIR spectra of SC and the physical mixtures of the drugs with each polymer, namely sodium deoxycholate, stearic acid, and Tween 80 (at a 1:1 w/w ratio), were obtained using a Thermo Scientific Nicolet iS-50 Fourier-transform infrared spectrometer sample holder

Proteomics 7 , 28332842 (2007)

These findings suggest that osteoblast-derived IGF-1 primarily exerts it anabolic effects by enhancing osteoblast efficiency and promoting osteocyte survival (Zhao et al., 2000)