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When symptoms do occur, they may include 7,46,47 : Debilitating fatigue Itching and numbness Headaches Muscle cramps Weight loss Sleep disturbances Lack of appetite Nausea and vomiting Shortness of breath Seizures Edema (swelling) of the extremities CKD is often discovered in people who do not have significant symptoms when they either attend their yearly physical and undergo lab testing or have blood work done for other reasons

Acknowledgements HZ and HW contributed equally to this work

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Research Overview Understanding BPC-157 BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide whose 15-amino-acid sequence was derived from a larger gastric protective protein first characterised by Predrag Sikiric and colleagues at the University of Zagreb in the early 1990s

(2023) 15(686):eabl4414

PMID: 7678769