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Endocrinology 135 , 10661072 (1994)

The combination of B12 plus PE1 has been shown to be more effective in improving symptoms and nerve conduction velocity (NCV) than either B12 72 or PE1 73 alone

This includes those with methylation disorders, cardiovascular conditions, and pregnant women or children

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Additionally, B12 and Vitamin C should be taken a few hours apart

Constipation, diarrhea, loss of appetite, or flatulence