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Emadis group also uncovered that reducing glutamine resulted in a decrease of the metabolite 2-hydroxybutyric acid (2-HG) and thus inhibited the proliferation of AML cells with isocitrate dehydrogenase (IDH) mutations [18]

The findings (Figure 6C) suggest that Lactobacillus and Akkermansia , which are considered potentially beneficial genera, exhibited a significant negative correlation with colonic pro-inflammatory cytokines (TNF-, IL-1, IL-6), MDA and serum LPS, and a significant positive correlation with colonic antioxidant indicators (GSH-Px, SOD)

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While IPA predicted overall activation of the White Adipose Tissue Browning pathway with a z-score of 3.13, it was predicted that there would be a decrease in mitochondrial biogenesis, differentiation of white adipocytes, and transdifferentiation of white adipose tissue to beige adipose tissue

Adaptogenic activity of a novel, withanolide-free aqueous fraction from the roots of Withania somnifera Dun