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Thus, ACs play a critical role in mitochondrial energy metabolism, essential for functioning of all tissues, as they transport long-chain fatty acids into mitochondria for -oxidation, a key energy production process [13]

Indeed, we have reported that decreased or absent HO-1 expression in peritoneal macrophages results in enhanced ROS formation and increased inflammatory cytokines such as MCP-1, interleukin 6 (IL-6), and the murine interleukin 8 homolog (KC

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The injection volume was 16 L, the column temperature was maintained at 40 C, and the flow rate was set at 0.3 mL/min

Blood 129 , 27192726 (2017)

In the middle with the green arrows at the top, you see how the hydrogen peroxide (H2O2), can be converted by the Catalase enzyme back to oxygen (O2) and water (H20) on the right