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DNA from the fresh-frozen samples was extracted in the same way as for the primary colon tumors

Additionally, the decreases in heart rate were not blocked by atropine, an anticholinergic agent, which indicates that the lowered heart rate was independent of parasympathetic activation [46]

Circulating levels of AGEs and soluble RAGE isoforms are associated with all-cause mortality and development of cardiovascular complications in type 2 diabetes: a retrospective cohort study