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A 500 mcg oral dose might deliver the biological equivalent of 50 mcg or less via injection

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The formazan crystals formed were dissolved in 200 L of solubilization solution (DMSO), and absorbance was recorded at 570 nm

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Your dose might be significantly less than intended, and the degradation products may cause unexpected reactions

In an open uncontrolled trial in 20 men with idiopathic infertility and a low testosterone-to-estrogen ratio, three months of treatment with letrozole resulted in improved sperm motility and morphology, reduced sperm DNA fragmentation, increased testosterone-to-estrogen ratio, and four spontaneous pregnancies