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Mean FIB-4 levels were 1.03, 1.4, 1.6, and 2.13 in group 1, 2, 3, 4, respectively (p 30%, infiltrative disease on liver biopsy, or pregnant

This improved vascularization creates a more favorable environment for the migration and proliferation of fibroblasts and other cell types essential for wound healing

Nature 577, 421425 (2020)

(24) investigated plasma mtDNA levels in RA patients and found that RA patients had a high sensitivity to mtDNA copy number compared to healthy controls, and also found that plasma mtDNA concentration was significantly correlated with the Disease Activity Score-28-Erythrocyte Sedimentation Rate (DAS28-ESR), which increased with the increase of DAS28-ESR, thus it is reasonable to believe that plasma mtDNA may be an inflammatory contributor as well as a biomarker in RA

However, to ultimately solve the problem of the ROS origin, T cell-specific knockouts of NOX-2 or other ROS-producing enzymes have to be used