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The Glutamate/Cystine Antiporter SLC7A11/xCT Enhances Cancer Cell Dependency on Glucose by Exporting Glutamate

In the absence of any validated diagnostic criteria, clinicians sometimes inappropriately use the Assessment of Spondyloarthritis International Society (ASAS) classification criteria for axSpA for diagnosis, and this is unfortunately perpetuated in part by the statement in the abstract of the original paper describing the final selection of these criteria that they may help rheumatologists in clinical practice in diagnosing axSpA in those with chronic back pain. The diagnostic approach in clinical practice is aimed at the estimation of the probability of a suspected disease based on the patients clinical history, physical examination, investigations and the exclusion of alternative explanations that are not included in the ASAS classification criteria

The gut barrier is supposed to keep potentially inflammatory proteins from entering our bloodstream, where they can trigger an immune response, even contributing to autoimmunity

McKenna Robert W

PMID: 33633208

Modern-day diets and food processing practices can reduce the amount of CLA we consume , which suggests that we could benefit from supplementing with this omega-6 polyunsaturated fatty acid