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De Candia et al., 2021)

The storage lesion is exacerbated in some categories of donors as a function of biology (sex, age) 21 , genetic traits 22,23,24,25 , and lifestyle-associated exposures 26 (comprehensively reviewed in 15,21,27,28

However, simple crossing of the SOD1G93A mice with mice overexpressing EAAT2 (to about a double of the normal level) resulted in an ALS model where the appearance of ALS signs and the onset of the motor neuron loss were only marginally delayed, with no effect on the final outcome [392]

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15C 3 month In solvent: -80C 6 months