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ABC transporter is responsible for accumulation and transmembrane transport of secondary metabolites and the most upregulated DEGs, as shown in Table 1 (3.4-fold) (Theodoulou and Kerr, 2015)

Several studies have pointed to PI3K activation as a pivotal event for estradiol effects, a common pathway for IGF-I and insulin [344]

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pH-Sensitive Formulations: Used in studies where neutral pH may cause peptide aggregation or degradation, particularly in compounds with complex tertiary structures

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