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This process avoids adding external molecules since interferon gamma (IFN-) and tumor necrosis factor-alpha (TNF-), two cytokines associated to the SASP, act as natural adjuvant by promoting an immunoreaction

About this article Cite this article Kulkarni, S.R., Thokchom, B., Abbigeri, M.B

There were cured jaundice, weight loss, liver enlargement, microscopy (i.e., piecemeal necrosis, focal lytic necrosis, apoptosis and focal inflammation, and disturbed cell proliferation (Ki-67-staining), cytoskeletal structure in the hepatic stellate cell (-SMA staining), collagen presentation (Mallory staining), and biochemistry presentation (Sever et al., 2019), and counteracted the increased NOS3 expression, interleukin (IL)-6, tumor necrosis factor (TNF)-, and IL-1 levels

Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were performed using The Database for Annotation, Visualization, and Integrated Discovery (DAVID) 48

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