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UK patients should understand that: Available evidence is largely from Phase 2 studies with relatively short follow-up periods Long-term cardiovascular outcome data are not yet available for either agent Phase 3 trials are ongoing, and results will inform future regulatory submissions to the MHRA UK patients interested in accessing these treatments through clinical trials may wish to consult the NIHR 'Be Part of Research' portal (bepartofresearch.nihr.ac.uk) or ClinicalTrials.gov for current recruitment opportunities

PROZAC should be introduced with care in patients with a history of seizures

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Upon further heating, they gradually soften, which can be characterized by certain softening points

Asthmas complex heterogeneity has led to the identification of distinct asthma clusters, or endotypes, that are defined by their shared clinical features, or phenotypes, shown in Fig

Statistical analysis All in vitro experiments reported here were performed in biological and technical replicates