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Further studies on the role of metabolites in ()-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity

Subcutaneous injection of EGCG in mice at doses exceeding 100 mg/kg/day induces severe hepatotoxicity and dose-dependent mortality, with higher concentrations leading to accelerated death

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10.1186/s13048-025-01737-9 Summary Keywords Ramulus mori (Sangzhi) alkaloids, PCOS, intestinal oxidative damage, inflammatorystatus, intestinal microbiome and metabolites, fenoldopam, bile acid metabolism Citation Wang Y, Jiang X, Wu S, Wang Q, Zuo D, Huang B, Jian L, Yang Y, Cai Y, Wen X, Yao L and Geng S (2026) Ramulus mori (Sangzhi) alkaloids improve intestinal oxidative damage and inflammation in DHEA-induced polycystic ovary syndrome rats via gut microbiota and metabolite modulation