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This suggests the involvement of the NF-B pathway in regulating GGT expression

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In this study, we show that nearly half of the human thyroid cancer specimens have increased GPX4 expression compared to control normal thyroid tissue and that the GPX4 overexpression is associated with worse overall survival

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Furthermore, several novel GLS inhibitors have exhibited superior therapeutic efficacy in clinical settings and preliminary studies, such as IN-3, have been shown to possess antiproliferative effects on PCa