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Decreasing the activity of complex II in respiratory chain of the affected brain regions causes striatal damage and motor phenotypes that are closely similar to symptomatic HD patients

Emerging studies have revealed that an increase in mitochondrial oxidative stress and mitochondrial dysfunction results in impairment of neurovascular during the aging process (Springo et al., 2015)

18 A major depressive episode always follows a traumatic or stressful life event

Allodi I, Nijssen J, Benitez JA, Schweingruber C, Fuchs A, Bonvicini G, et al

During the development of CRC, the expression of key enzymes involved in processes such as fatty acid synthesis, uptake, and oxidation is often increased

doi: 10.1158/1535-7163.MCT-23-0809