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Wang, Z.S., Gu, Y.X., and Yuan, Q.S., Curr

In addition, the AGE-RAGE interaction further instigates pericyte apoptosis, vascular inflammation and permeability, and blood-tissue barrier breakdown 56

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The advent of iPSC technology has been instrumental in developing the field of gene therapy for FRDA, with studies utilising FRDA iPSC-derived models to investigate potential gene targets as well as exploring the effectiveness of various vectors of delivery (see Table 3)

Results: We included 51,452 NAFLD patients in the prevalence cohort and 37,027 in the incidence cohort

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