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an inhibitor of GCL and consequently of glutathione synthesis) enhanced ferroptotic cell death induced by all ferroptosis-inducing compounds, and its modulation effect is specific to ferroptosis-inducing compounds

Treatment-induced neuroendocrine prostate cancer and de novo neuroendocrine prostate cancer: Identification, prognosis and survival, genetic and epigenetic factors

Cell death was measured by counting maximum SYTOX TM Green positive cells normalised to starting cell confluence (B) from images generated by IncuCyte ZOOM software

Rotating injection sites and using proper technique minimizes these effects

Gao W, Chen L, Lin L, Yang M, Li T, Wei H

Because GPX4 ablation or inaction is embryonically lethal, only heterozygous or conditional knockout mice can be analyzed (Table 1)