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Curcumin induces apoptosis in lung cancer cells by 14-3-3 protein-mediated activation of Bad

The major findings are that aerobic glycolysis is not a symptom of impaired mitochondrial function, and that glutamine supports mitochondrial oxidative metabolism when pyruvate derived from glucose is converted into lactate and secreted 2,3,4

6.3 Crosstalk between the glutathione and thioredoxin systems The glutathione (GSH/GR/GPx) and thioredoxin (Trx/TrxR/Prx) systems constitute the two primary thiol-based antioxidant defenses in cells