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As oxidative stress can be involved in the etiology of hypertension and cerebrovascular disease, polymorphic genes encoding for GPxs can be putative candidates for the genetic susceptibility to CS

To date, no alterations in the FLNA gene CpG island with the highest probability to have regulatory functions have been found, excluding an epigenetic silencing ( FLNA Regulates SSTR2 Expression and Signaling in GH-Secreting Pituitary Tumors In addition to DRD2, FLNA seems to have a critical role also in the regulation of SSTR2, with important implications for SS responsiveness in acromegalic patients

Analyses of the patterns of epigenetic alteration are providing important insights into the origin of this disease and have identified specific alterations that may serve as useful diagnostic and prognostic biomarkers

Glycerophospholipid metabolism is significantly different in metabolomics and lipidomics data between AMD and normal RPE

Control Release 363 , 180200 (2023)

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