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Associated with migraines (headaches and abdominal)

Several factors have been implicated in the cause of Crohns disease, including a dysregulated immune system, an altered microbiota, genetic susceptibility and environmental factors, but the cause of the disease remains unknown

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Organotypic hippocampal slice cultures (OHSC) Mice (P6-8) were decapitated, brains were aseptically removed, and hippocampi were dissected under sterile conditions in ice-cold isolation buffer (pH 7.2) containing Gey's balanced salt solution (Thermo Fisher Scientific, Dreieich, Germany, #J67569.K2), 1 mM kynurenic acid (a NMDA receptor antagonist

Endogenous checks and balances exist within this information flow, which can be leveraged as therapies to treat diseases closer to their genetic origin