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Dietary sources like Brazil nuts, fish, and grains supply this mineral, and maintaining optimal levels supports the enzymes role in detoxifying reactive oxygen species

355 The pro-inflammatory cytokines, in turn, augment both mitochondrial and NOX-generated ROS, contributing to further accumulation of oxidative damage (Fig

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Subsequently, we apply a novel, high-resolution Consensus GPT scoring method to these top candidates, providing a more nuanced, reference-backed evaluation

hLMNA-WT/R482L myoblast cell-type specific gene expression To find hLMNA-R482L-induced alterations in gene signatures we performed differential expression analysis between hLMNA-WT and hLMNA-R482L myoblasts in each cluster followed by analysis of pathways associated with differentially expressed genes (DEGs) enriched in clusters

Mn-SOD, located in the mitochondria, and Cu/Zn-SOD, primarily found in the cytoplasm, play crucial roles in antioxidant defence