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Name: acetyl l-carnitine autism reviews Frontiers ACETYL-L-CARNITINE - Neuroneeds
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NRF2 signaling pathway The transcription factor NRF2 is a master regulator of the antioxidant response and a key target for inhibiting ferroptosis in individuals with DACI

Oxidative DNA adducts such as 8-oxoG are not only lesions but also contextual signals that recruit base-excision machinery (e.g., OGG1) and remodel local chromatin, thereby coupling genome surveillance to transcriptional tuning

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N-Acetyl-L-Cysteine (NAC) is an amino acid that is a precursor to glutathione, the bodys most powerful antioxidant, which helps support optimal liver detoxification, lung health, antioxidant status, and muscle recovery

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This network underscores the essential role of bidirectional microbiotametaboliteimmune crosstalk in SLE and provides a rationale for targeted interventions (such as FMT, probiotics, metabolite supplementation, etc.), aiming to restore immune homeostasis through multiple pathways (Fig