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6), whose inhibition reduces cytokine secretion and FLS proliferation, making it a potential therapeutic target

Sun exposure is the largest environmental accelerant of skin aging, primarily through UV-driven DNA damage in keratinocytes and free radical generation that degrades collagen

Zielsdorf also initially puts patients on an oligoantigenic elimination diet (a diet that limits the foods eaten to a very narrow list of foods that are not likely to cause reactions), which usually follows the Autoimmune Paleo template