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Comparative Trials Head-to-head data suggest tirzepatide (Zepbound) achieved ~20.2% mean weight loss at 72 weeks versus ~13.7% with semaglutide (Wegovy)

Sci Rep 16 , 18201 (2026)

Rossini M, Di Munno O, Valentini G, Bianchi G, Biasi G, Cacace E, Malesci D, La Montagna G, Viapiana O, Adami S: Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients