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A lot of the research is still early-stage, and while interest is growing, there's still more to learn - especially when it comes to long-term use in humans

Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin

Furthermore, BHB influences adipocytes by upregulating uncoupling protein 1 (UCP1) and PR domain containing 16 (PRDM16) via the AMP-activated protein kinase(AMPK)/SIRT1/PGC-1 pathway, resulting in reductions in body weight and lipid levels [112]

Nevertheless, much of the available evidence is still derived from in vitro experiments

Lu, Q., Zhang, X., Liang, T

10.1016/j.jaad.2016.03.001 150 LeeM.-H.KimH.-J.HaD.-J.PaikJ.-H.KimH.-Y