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Malic enzymes 1 (ME1) and 3 (ME3) generate NADPH in the cytosol and mitochondrial matrix, respectively

doi: 10.1155/2021/7157109 97 NolanDMallalS

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Ding R, Ma Y, Li T, Sun M, Sun Z, Duan J

The claim that the former causes the latter is a well-supported hypothesis that nobody has closed with a head-to-head comparison worth knowing, given that this is the central premise of every DAC-versus-no-DAC explainer, including this one