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Distant metastases form monophyletic groups and have reduced clonality compared to LN metastases, suggesting different evolutionary mechanisms between LN metastases and distant metastases (154)

Enhancing FAO via LCA supplementation (the cofactor of CPT1B), attenuated cardiac steatosis and lipotoxicity-induced pathological changes in the atria of obese mice, resulting in restored AF substrates and ameliorated AF susceptibility (Figure 7)