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If susceptible mouse strains are used in research, the more severe diffuse lesions may occur

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We compared human aortic smooth muscle cells (HASMCs) with and without CRISPR-Cas9 editing of the Loxl2 gene (HASMC T1) to test whether LOXL2 depletion correlates with loss of BHZ incorporation signal and to determine the specificity of the assay