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Agronomy 3 (2), 433461 (2013)

Alcohol is a triple threat: it contains histamine (especially wine and beer), it inhibits DAO activity, and it increases intestinal permeability (allowing more histamine to enter circulation)

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It increases the proportion of slow-wave sleep (delta, 0.5-4 Hz) without suppressing REM sleep, unlike GABAergic hypnotics

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Females are twice as likely to receive MS as males [3]