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Herein, the optimization pathways of existing therapeutics and emerging therapeutic directions are systematically reviewed, with particular emphasis on their mechanisms of action, current clinical application status, and future potential, with the aim of providing guidance for personalized IBD management

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Notably, even though acetylation modification exists on GCLC, its level is not affected by manipulating SIRT2 expression

(iii) Stem cellstoxicological tests involving the insertion of disease genes into embryonic stem cells, which then differentiate into human disease tissues that can be further used for drug screening

A post-time of 8 min was set to allow the system to equilibrate to the initial condition of 5% A before further injections

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