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The main controversy with Kashin-Beck disease being linked to Selenium deficiency is that the pathogenesis is likely multifactorial in nature

a, b, c, d Liu, L., Zhou, W., Guan, K., Peng, B., Xu, S., Tang, J., Zhu, Q., Till, J., Jia, X., Jiang, C., Wang, S., Qin, Z., Kong, H., Grant, R., Mezbahuddin, S., Kumar, V., and Jin, Z.: Knowledge-guided machine learning can improve carbon cycle quantification in agroecosystems, Nature Communications, 15, 357, 2024

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I take responsibility for what I did, but unlike the vast majority of people in this sport I did something about it." Ironically, it would be Magness who would find himself on the wrong end of a potential ban for his part in Salazar's L-carnitine experiment

(2000) Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells

Any sort of elevated intracellular ROS concentration contributes to various pathological conditions (Figure 1)