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Supports investigation of tissue structural rejuvenation: Accumulated senescent cells can impair tissue architecture by altering cell-to-cell communication and extracellular matrix composition

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HSS Journal (2025) 8

Researchers hypothesize this may influence: NAD metabolism methylation pathways cellular energy balance adipocyte metabolism Q12: Does it affect fat cells directly

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The assessment of results was made at 24 and 96 hours after peptide administration and included changes in the kidneys on a scale from 0 to 3, where: 0 - healthy kidney, 1 - mild hydronephrosis, 2 - moderate hydronephrosis, visible dilation of the renal pelvis, few changes on the kidney surface, 3 - severe hydronephrosis, dilation of the renal pelvis, thinning of the renal parenchyma, and a significant number of changes on the kidney surface