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Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K (2004) Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

Direct inactivation of the enzyme tyrosinase Switching off the production of the Eumelanin (gives darker complexion) Switching on the production of the Pheomelanin (gives brighter complexion) Sun exposure and oxidative stress can disrupt melanin levels, leading to an increase in Eumelanin for a darker complexion, and a decrease in Pheomelanin, resulting in a brighter tone

Keep the soap on your skin for at least 60 second and then wash it off

Mulberry leaf water extract (MLWE) was found to play a key role in regulating lipid metabolism disorders at the genetic level by down-regulating genes involved in oxidative stress, such as acetyl coenzyme A carboxylase and fatty acid synthase while up-regulating peroxisome proliferator-activated receptor (PPAR), which encodes the PPAR

Nature communications, 7(1), 12948

Trichloroacetic acid (TCA) is applied to the hyperpigmented areas with a cotton swab and left for a duration depending on the patients skin type