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Therefore, mechanistic evaluation of nano-phytomedicines should differentiate between attenuation of oxidative damage and modulation of redox-dependent signaling cascades, particularly those governing neuronal survival and mitochondrial homeostasis

Of the 18 children identified to carry high confidence variants, 14 had formal cognitive assessment with profiles ranging from an average full-scale IQ (FSIQ) ( n = 3), to borderline FSIQ results ( n = 6), to mild intellectual disability ( n = 5)

Shetty AS, Bhatia KP, Lang AE

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Additionally, the presence of melatonin receptors in ocular tissues highlights the potential for targeted therapeutic interventions through topical administration, leveraging these receptors to elicit beneficial effects (76)

Aoyama K, Matsumura N, Watabe M, Nakaki T (2008) Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction