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Licata, L

In the last few years, various GSH modulation-enhanced combinational therapy strategies have been extensively exploited, accompanied by the development of versatile metal-based nanosystems with different structures, functionalities, and treatment performances ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)

Four different types of human glioma cell lines (LNT-229, LNT-308, LNT-428, and G55) were treated with selective mGluR5 antagonist (MPEP), mGluR1-specific antagonist (CPCCOE), and group I mGluRs (mGluR1 and mGluR5) agonist DHPG as a negative control

In unstressed plants ONOO was continuously scavenged by PrxIIE, which was inhibited by S-nitrosylation in course of the HR (Romero-Puertas et al., 2007)

While MCP works systemically in the bloodstream, chlorella provides essential detoxification support in the gastrointestinal tract

Its antimicrobial properties support immune function, while its anti-inflammatory effects may help alleviate acne and eczema