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The medication is FDA approved to treat hypoactive sexual desire disorder (HSDD) in premenopausal women

OMIM 236250) deficiency is a rare inborn error of metabolism and inherited in an autosomal recessive fashion

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The dose of LT4 required by a patient can be predicted from the total body weight, the body mass index (BMI), ideal body weight, and lean body mass, with the latter three parameters providing the most accurate estimates