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Bisphenol-A treatments upregulate the levels of Drp-1 in NSPCs in vitro and in the rat hippocampus, leading to decreased elongated mitochondria, abnormal cristae depletion, apoptosis, and consequently loss of NSPCs proliferation/differentiation balance

Francisco-Cruz, A, Rocha, P, Reuben, A, Krishnan, S, Das, P, Chen, R, Quek, YK, Li, J, Parra Cuentas, ER, Solis Soto, LM, Barua, S, Jiang, M, Segura Lazcano, R, Chow, CW, Behrens, MC, Gumb, C, Little, L, Fukuoka, J, Kalhor, N, Weissferdt, A, Kadara, HN, Heymach, JV, Swisher, SG , Sepesi, B, Uppore Kukkillaya, AR, Moran, C, Zhang, J, Lee, JJ, Fujimoto, J, Futreal, A, Wistuba, II, Peterson, CB, Zhang, J

Clinics often administer 600 mg to 1,400 mg per IV session, 1-3 times a week

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Pharmacometabolomics Pharmacometabolomics, also known as pharmacometabonomics, identifies nongenetic, environmental factors (e.g