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This combination delivers a potent dose of vitamin B12 for increased energy and mental clarity, along with MIC Slim Shots to support fat metabolism and liver health

Causes of High Homocysteine Levels (Hyperhomocysteinemia) Many factors contribute to high homocysteine levels: Insufficient folate, vitamin B 6 , vitamin B 12 , betaine, vitamin B 2 , and magnesium Certain prescription drugs (including cholestyramine, colestipol, fenofibrate, levodopa, metformin, methotrexate, high-dose niacin, nitrous oxide, pemetrexed, phenytoin, sulfasalazine) High-methionine diet (including red meat and dairy products) Smoking High coffee consumption Alcohol consumption Advancing age Obesity Genetic variant that causes an impaired ability to metabolize active folate from folic acid Note: Life Extension believes that the optimal range for homocysteine levels is 11 mol/L) has been associated with a substantial increase in risk of dementia in the elderly

At the molecular level, preclinical models have suggested a multimodal mechanism

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240 Vitamin C Vitamin C is a water-soluble antioxidant and has demonstrated an ability to reduce platelet aggregation and promote fibrinolysis, without impacting coagulation pathways, in high-oxidative stress pro-thrombotic conditions in the laboratory

Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review