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Moreover, eryptosis has been demonstrated to be induced by NPs [459] or high-molecular-weight polysaccharides [494] without their uptake but with accumulation around the cells, suggesting that eryptosis might be induced by shear stress via piezo1 mechanosensitive Ca 2+ ion channels

165 Crosstalk in disease contexts: a unified perspective The crosstalk between proteostasis machineries is particularly relevant in the context of disease

This trial found that FUS in one hemisphere improved motor features of Parkinsons disease as evidenced by a decrease in Unified Parkinsons Disease Rating Scale (UPDRS) scores, although some adverse events were reported including speech and gait disturbances and weakness on the treated side

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