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Collagen synthesis and remodeling occur slowly compared to other biological processes

Loss of NAD + levels results in impairment of mitochondria function, which leads to failure of essential metabolic processes (Klimova and Kristian, 2019

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We speculate that the BPC157-FBXO22 interaction via P3 delays enzymatic degradationpeptide catabolism typically initiates with endopeptidases, followed by stepwise proteolysis into amino acids